Ankylosing spondylitis is a chronic systemic disease that seriously affects the human skeletal system. The most significant changes are fibrosis and bony ankylosis of the joints, and even loss of mobility, so what types of people should be alert to ankylosing spondylitis in their lives? The first group of people who are prone to ankylosing spondylitis has a higher incidence in men than in women, and the incidence is higher in men between the ages of 20 and 30; it is rare in children over the age of 40 and under the age of 8. According to research, HLA-B27 positive patients are at risk of developing ankylosing spondylitis after diarrhea, dysentery or urinary tract infections, especially those with a family history of ankylosing spondylitis, and young men between the ages of 20 and 30 are at risk of developing ankylosing spondylitis after recurrent intestinal, diarrheal, dysentery or urinary tract infections, especially those with a family history of ankylosing spondylitis. Patients with a family history of ankylosing spondylitis are at greater risk. The second group of people who are prone to ankylosing spondylitis are those who have low back pain, especially stiffness in the morning that is relieved by activity, or inflexibility of the lower back, and therefore need early prevention to avoid the development of ankylosing spondylitis, which can affect your health. If these symptoms occur, you should seek medical attention for early diagnosis and treatment to prevent the development of spinal ankylosis and deformity. The third group of people with degenerative sacroiliac joints. The sacral vertebrae and coccyx degenerate during the evolution of human beings, and individual differences are relatively large. The sacral vertebrae and the ilium form the sacroiliac joint, which is connected mainly by cartilage and participates in forming the pelvis. Therefore, early prevention of ankylosing spondylitis is required for patients with degeneration of the sacroiliac joint. Once signs of ankylosing spondylitis are detected, they need to be treated early. The dangers of ankylosing spondylitis Ankylosing patients may suffer from lifelong disability if they are not treated in a timely manner or if they are not treated properly. 1, because the disease generally first invade the sacroiliac joint, and then gradually up the spine, and involving the lumbar, thoracic, and even cervical vertebrae, the affected spine not only appear low back pain, and may appear progressive activity restrictions; some form different degrees of hunchback deformity, serious people not only mobility, and both eyes can only look at the ground, and the disease about 60% of the hip joint can be involved, it not only can make the hip joint gap become It can not only narrow the hip joint gap, but also cause serious pain in the hip joint due to bone destruction, and the patient cannot do flexion and extension activities of the hip joint, which will lead to the formation of bony ankylosis of the hip joint and the loss of activity function, resulting in lifelong disability. 2, due to damage to the hip joint and disability accounted for about 30% of the hip joint change, the total disability rate of about 15% to 20%, only about 60% of patients can maintain the ability to work and live, but there are various degrees of discomfort, pain and inconvenience throughout life. The danger of ankylosing spondylitis is very great, for ankylosing spondylitis or early detection, early treatment is good.