Ankylosing spondylitis is a chronic inflammatory disease, which belongs to rheumatic immune diseases. This is a good way to slow down the progression of the disease and improve the prognosis, but the liver and kidney function should be reviewed regularly during the medication period. 3.Anti-rheumatic drugs that relieve the symptoms of the disease are mainly used for drugs that are contraindicated for anti-tumor necrosis factor and combined with peripheral arthritis, such as lorazepam, methotrexate, thalidomide, etc. 4.Glucocorticoids, glucocorticoids are generally not used for the treatment of this disease. Glucocorticoids are generally not used for the treatment of this type of disease, but only for local use, such as strong spine combined with peripheral arthritis, tendon terminal disease, etc.