What is the most effective medicine for gout

  Gout is a relatively common metabolic disease, with a prevalence in middle-aged men and a tendency to have a lower age of onset. At present, there are many drugs for the treatment of gout. The drugs used in the acute phase are mainly to inhibit inflammatory reaction and relieve pain, while the remission phase is mainly to reduce blood uric acid.  Acute phase: the commonly used drugs are: 1, non-steroidal anti-inflammatory drugs, such as indomethacin, diclofenac sodium, etc., which can effectively relieve the symptoms of acute gout; 2, narcotic; 3, glucocorticoids: for patients with poor effect or intolerance of the above two types of drugs, they can be taken orally or injected for a short period of time, which has obvious efficacy in treating acute gout.  In remission: In order to maintain blood uric acid levels and prevent acute attacks of gout in remission, oral uric acid-lowering drugs are needed. There are two main types of drugs in common use: 1) xanthine oxidase inhibitors, which reduce uric acid synthesis by inhibiting xanthine oxidase, such as allopurinol and febuxostat; 2) drugs that promote uric acid excretion, which reduce uric acid reabsorption by the renal tubules, thereby increasing uric acid excretion and reducing blood uric acid. Others such as sodium bicarbonate can alkalize the urine and have an auxiliary effect on the treatment.  In addition, it is also important to pay attention to the dietary habits as well as the regulation of living habits in life. Weight control, proper exercise, avoiding alcohol and high purine diet, drinking more water, eating more fresh vegetables and supplementing plant fiber. Long-term monitoring of blood biochemical indicators is also an important part of the treatment.  In conclusion, gout is a chronic and lifelong disease that requires attention and active treatment, but specific medication needs to be administered under the guidance of a doctor.