According to the “Novel Coronavirus Pneumonia Diagnostic and Treatment Program (Trial Ninth Edition)”, the available evidence suggests that the Omicron strain is more transmissible than the Delta strain, with reduced pathogenicity. It is recommended to continue to take precautionary measures and avoid going to crowded places as far as possible. Neocoronaviruses have been mutating, and some strains have mutated in ways that affect their immune escape ability, pathogenicity, and infectiousness. However, according to the “Diagnostic and Treatment Program for Neocoronavirus Pneumonia (Trial Ninth Edition),” the available evidence shows that the Omicron strain is more transmissible than the Delta strain, but its pathogenicity has weakened. Although the pathogenicity of the new coronavirus has been reduced, it can still cause damage to the body and can still cause pneumonia, resulting in severe symptoms such as pulmonary fibrosis and respiratory distress, and therefore active prevention is still needed. The new coronavirus is still mutating, it is recommended to do a good job of personal protection, wear a good mask, and try to avoid going out. Tip: “New coronavirus pneumonia” and “new coronavirus pneumonia” mentioned in this article were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.