The liver is capable of regeneration, and the capacity and potential for regeneration is very high. Animal experiments have also demonstrated that even if 70-80% of a normal liver is removed, the normal physiological function of the liver can be maintained, and it can gradually return to its pre-surgical liver weight in about six weeks. However, the human has a relatively poor regenerative and repair capacity, but it can still return to its pre-surgical weight in about a year. Because of this characteristic of the liver, liver segmentation, lobectomy, or even an enlarged hemihepatectomy may be considered when there are limited lesions in the liver and can allow the patient to achieve radical treatment in a safe manner. However, an evaluation of liver function should also be performed prior to liver surgery to determine if the extent of resection can be tolerated. Especially in patients with previous chronic liver disease and cirrhosis, the extent of resection should also be done with caution to minimize the number and duration of intraoperative hepatic hilar blockage to avoid postoperative liver failure, as the regenerative and repair capacity of the liver is greatly compromised.