The decision to immediately hospitalize a person with leukemia depends on the type of leukemia and the patient’s symptoms. Acute leukemia with severe symptoms is recommended to be hospitalized, while chronic leukemia with mild symptoms may not be hospitalized. 1. Acute leukemia often starts rapidly with fever, worsening anemia, bleeding, bone and joint pain, and enlargement of the liver, spleen and lymph nodes. A few patients may start with headache, vomiting, stiff neck, convulsions, blindness, toothache, swollen gums, chest tightness (which can be caused by pericardial effusion), and paralysis of both lower limbs, etc. This condition requires prompt hospitalization. Therapeutic drugs include cytarabine and Zoerythromycin. 2. Chronic leukemia often has no obvious changes in the early stage, and many people only find out about it during medical checkups or when they go to the doctor for other diseases. Chronic leukemia progresses slowly, and it takes a long time before symptoms such as fatigue, low-grade fever, excessive sweating or night sweating, and weight loss appear. Chronic leukemia starts slowly and the symptoms are mild, so some patients can be treated with out-of-hospital medications and regular outpatient reviews. Therapeutic drugs include nitrogen mustard phenylbutyrate, ibrutinib, imatinib and so on. When leukemia is detected, patients should receive regular treatment under the guidance of a doctor.