Disordered and peculiar behavior is one of the clinical manifestations of mental disorder associated with intracranial tumor. Mental disorder associated with intracranial tumor refers to the mental disorder associated with the invasion of brain parenchyma by intracranial tumor and compression of adjacent brain tissues or cerebral blood vessels, resulting in the destruction of brain parenchyma or increase of intracranial pressure, and about 40% to 100% of patients suffering from intracranial tumor can develop mental symptoms. How to effectively prevent behavioral disorders while peculiar? It is important to maintain a relatively calm state of mind. Combination of work and rest, scientific brain, a certain amount of pressure can stimulate interest in learning to improve learning efficiency, which is beneficial to psychological health, people in real life, does not depend on the subjective will of the person, as long as the individual is required to fully understand and understand reality, adapt and transform reality. This requires adolescents to face reality and unite their personal ideological wishes and requirements with the real society. For patients diagnosed with brain tumor, more social and family psychological support and assistance should be given, which is expected to alleviate the symptoms of mental disorders associated with brain tumor. Early detection and early treatment are the principles of treatment for all diseases, and the treatment of intracranial tumors is no exception. The earlier the treatment, the better the results. Treatment methods include surgery, radiotherapy, chemotherapy, Chinese herbal medicine, immunotherapy, etc. Anti-psychotic drugs with high efficiency and low toxic side effects should be selected for psychiatric symptoms. The dose of medication should not be too high, especially in the postoperative period and in radiotherapy and chemotherapy, and patients with epilepsy should monitor the blood concentration. The treatment of intracranial tumors in general is based on surgical removal, which should be performed as early as possible once the diagnosis is confirmed. Surgery can improve somatic and neurological symptoms. Some malignant tumors, such as metastatic carcinoma and highly infiltrative glioblastoma multiforme, are generally not considered for surgical treatment if surgery can cause brain tissue edema and lead to increased functional disability. If it is an isolated cancer, it can be resected. Radiation therapy and chemotherapy need to be administered under the guidance of appropriate specialists, and chemotherapy is known to be effective for intracranial sarcomas. Some symptoms are associated with cerebral edema and dexamethasone is effective. Regardless of the type of tumor or prognosis, physicians should give patients and their families a high level of care and emotional support. Appropriate psychotropic drugs should be given to control psychiatric symptoms such as anxiety, depression, excitement, irritability, and xylophobia. The dose should not be too high, because patients with organic brain diseases have low tolerance to drugs. Short-term administration of antipsychotic drugs, such as fenadine, chlorpromazine, etc. Note that they should be given in conjunction with decompression measures, as these psychiatric symptoms are caused by increased cranial pressure.