Levofloxacin is a very commonly used antiseptic drug in clinical practice and is not able to treat allergic rhinitis. Allergic diseases are triggered by allergic reactions and often require the application of anti-allergic drugs for symptomatic treatment, which are commonly used clinically as lupatadine fumarate tablets and epastine tablets, and patients are advised to apply them selectively. If patients have nasal congestion, sneezing and runny nose when they have a cold, they can apply levofloxacin capsules and levofloxacin tablets for treatment, and drink more water after using the medication to promote the absorption and metabolism of the medication. Patients are advised to exercise more in life to improve their resistance to avoid allergic rhinitis, minimize the application of antibiotics, and consider going to the hospital for further consultation when necessary.