Monkeypox is a zoonotic infectious disease caused by monkeypox virus infection, the treatment is symptomatic support and treatment of complications. 1. Symptomatic supportive treatment: bed rest, pay attention to replenish water, maintain the balance of water and electrolytes in the body, physical cooling is the main, if necessary, if the temperature is more than 38.5 degrees, can be given to antipyretic and analgesic drugs to reduce fever. 2. Treatment of complications: secondary skin bacterial infection can use antibacterial drugs; corneal lesions, can apply eye drops, encephalitis, sedation, dehydration, lowering cranial pressure and other treatments. If you have traveled to a monkeypox infected area or suspect that you have monkeypox, please go to the hospital immediately to avoid delay in treatment.