1, the main cause of anal fissure is dry stool, the toilet struggle, the anus is torn by hard stool, and over time, the formation of chronic ulcers. Therefore, the stool should be kept open, after the formation of dry hard stool, do not struggle to discharge, you can choose warm saline enema, or paraffin oil enema, or injected into the anus with open cork, slippery defecation. 2, timely treatment of anal cryptitis, to prevent the formation of ulcers and subcutaneous fistula after infection. 3, women should pay attention to hygiene during menstruation, do not participate in heavy physical labor. During pregnancy, they should eat more fruits and vegetables to prevent constipation. Pay attention to protecting the perineum during childbirth and do not tear the perineum and anus. 4, in the anal examination such as anal finger diagnosis, with anoscope or other instruments should not be rough force, to prevent damage to the anal canal caused by anal fissure. 5, timely treatment of Crohn’s disease, ulcerative colitis and other intestinal diseases to prevent complications of anal fissures.