The fat filler normally done refers to granular fat, which is extracted from oneself and then processed by resting, centrifugation or concentration to fill the tissue and restore its volume. Later, with the advancement of technology, the latest fat grafting filler technique, nanofat, directly translated as nano-fat, was first published in 2014 by Professor Patrick Tonnard in PlasticandReconstructiveSurgery, a top plastic surgery journal, and is essentially further refined fat particles, which are injected by pushing through a syringe . After the filtering of the screen and the crushing of the blade, the fat particles are made finer and the survival rate is further improved. However, as the number of cases increased, we found that there was still more oil in the nano-fat, which sometimes led to local swelling and affected the survival of the fat. Based on the nano-fat, the researchers further centrifuged and refined the fat to purify the fat gel, which actually means that all the useless parts of the cytoplasm are removed and turned into oil, while the useful various stem cells are retained, of which the main component is the SVF multi-cellular consortium, but its purification efficiency is relatively poor, generally only 1 ml can be purified from 10 ml, which can be used in local filling Therefore, I generally recommend fat gel for filling fine areas, such as the hollows of upper lids and neck lines. However, when many friends hear that fat gel is so good, they often ask me how much it costs for full facial filler. In fact, fat gel is not suitable for large-scale filling, the purification efficiency is too low and too much fat is wasted, so when doing large-scale fat filling, it is usually better to use granular fat.