Whether the loss of one kidney will affect life expectancy depends mainly on whether the other kidney is functioning normally. For patients with normal renal function, the loss of one kidney usually does not affect life expectancy; however, for patients with renal insufficiency, having only one kidney may aggravate the burden on the kidneys, resulting in obstacles to the elimination of metabolic wastes and water from the body, which may affect life expectancy. The kidney has a strong compensatory function, and usually, one kidney can maintain the normal secretion and excretion of the organism. Therefore, for patients with normal renal function, the loss of one kidney usually does not affect life expectancy. However, it is still necessary to do a good job of protecting the kidneys to avoid damage to the normal kidneys. However, for patients with renal insufficiency, having only one kidney left may increase the burden of the kidney, resulting in impaired excretion of metabolic wastes and water from the body, symptoms such as oliguria, edema, hypertension, nausea, vomiting, loss of appetite and other symptoms, and in severe cases, manifestations such as life-threatening acute left heart failure may occur. This condition may affect life expectancy. If the patient loses one kidney, it is recommended to visit regular hospitals for regular medical consultation, so that specialized doctors can prescribe kidney function related tests and evaluate the test results.