High lower pressure also means high diastolic blood pressure. There are two main causes of high diastolic blood pressure, one, increased peripheral vascular resistance. Second, an increased heart rate. In addition to this, it can also be caused by an unknown cause, or by a family genetic cause. High diastolic blood pressure can lead to proteinuria, kidney damage or even kidney failure, uremia, and possibly fundus lesions and eye blindness. The damage to the heart can mainly cause changes in heart morphology, making the heart hypertrophic and enlarged, which can lead to symptoms of heart failure. In addition, there is also the possibility of peripheral arteriosclerosis, resulting in myocardial infarction, so the danger of high diastolic blood pressure is very high, long-term hypertension may also be a brain infarction or brain hemorrhage at any time, life-threatening situation.