For 0.4cm gallbladder polyps, usually no special treatment is needed and regular follow-up observation is sufficient. Gallbladder polyp is a protruding or elevated lesion on the wall of the gallbladder, which can be spherical or hemispherical, and most of them are benign and a few of them are malignant. Most patients are found in ultrasound or ct examination, usually no obvious symptoms, a few patients may have nausea, abdominal pain and other symptoms. For gallbladder polyps with a diameter of 0.4 cm, if there are obvious symptoms such as abdominal pain and nausea, which cannot be explained by other reasons, cholecystectomy is feasible for treatment, and if there are no symptoms, no treatment is needed. When there is a risk of malignancy, such as age greater than 50 years, primary sclerosing cholangitis, and non-tendinous polyps, 0.4-cm gallbladder polyps can be followed up for review at 6 months and then annually for the next 5 years. If there is no risk of malignancy, the polyps are followed up once after 1 year, once after 3 years, and once after 5 years to monitor polyp changes. When gallbladder polyps occur, it is recommended to seek prompt medical attention for rational and standardized treatment under the guidance of a physician.