The skull is the hardest bone in the human body and one of the most important bones. The role of the skull in the human body is significant because it is the direct protective barrier of the brain, the commander of the human body, protecting the brain tissue and intracranial organs from external damage, while maintaining a normal and stable intracranial environment and guaranteeing the operation of intracranial life activities. Without the protection of the skull, our brain tissues are exposed and are at risk minute by minute if they are damaged by trauma or other causes. Many people suffer from cranial defects due to various reasons, resulting in cranial collapse, which is extremely unattractive and can also cause many neurological impairments. After skull defect, patients will choose skull repair, and the choice of material is also a point of concern, as choosing the right material is beneficial for life. However, at present, some repair materials can cause rejection in human body, which not only can cause skin abrasion, but also can expose the repair material, which is not good for patient’s healing later, and also can easily affect patient’s emotion, which makes many patients and family members of cranial bone repair very troubled. The patient had an epidural hematoma caused by a car accident and was sent to a local hospital for hematoma removal + decompression of the bone flap, and the patient recovered for more than a month after the surgery and was discharged from the hospital, but the skull defect was left behind. The patient felt that the cranial defect brought great trouble to himself, both in appearance and psychologically, and caused great harm and serious psychological shadow. But he wanted to go back to work as soon as possible, so he chose the titanium mesh material locally in the repair, and the patient was very satisfied after the repair. Cranial repair surgery has become a very routine and mature clinical procedure, but the choice of material for the surgery is very important. Indeed, titanium mesh is still a widely used repair material in clinical practice, but because it is a metal material, the natural material has poor plasticity and cannot fit precisely with the defect of the patient’s head; in addition, a series of problems may occur after surgery, such as depression, exposed titanium mesh, and CT examination artifacts interfering with the diagnosis. The scientific name of peek material is polyether ether ketone material, which is known as the material equivalent to human skull. After 3D processing, it can achieve a perfect shaping effect and fit the surrounding cranial bone parts. In addition, it is resistant to high temperature and poor heat conduction, so there is no restriction to do examination after peek material skull repair, and the image will be clearer when CT examination is done, and the perfect degree of shaping can be seen.