In vitro can be done for severe oligozoospermia. IVF refers to in vitro fertilization, and with severe oligozoospermia, high quality sperm can be selected for IVF. Couples who choose IVF, if the male presents with severe oligozoospermia and teratozoospermia, need to screen the extracted male semen and select the high quality sperm from it to be specially cultured with the female’s eggs, and the high quality sperm will combine with the high quality eggs to form a fertilized egg or blastocyst, which will be sent to the female’s uterine cavity for development. In the case of severe oligozoospermia in male patients, they need to go to the local public formal medical institution’s reproduction center for IVF.