Oropharyngeal swabs are taken mainly from the pharynx, i.e. the posterior pharyngeal wall and the tonsils on both sides. Oropharyngeal swab collection should pay attention to oral hygiene, it is recommended to gargle in advance, and then try to open the mouth to expose the pharynx and throat, use the pharyngeal swab in the pharyngeal and palatal arches to wipe back and forth, to increase the contact area, and avoid contact with the mouth and tongue and other parts of the collection process. Before collection, attention should be paid to strengthening personal protection by wearing a mask and keeping a distance of more than one meter, and avoiding a full meal before collection, so as to avoid the pharyngeal swab from stimulating the posterior pharyngeal wall and causing symptoms such as nausea and vomiting. Oropharyngeal swab collection should be operated by a professional doctor to avoid personal improper operation affecting health.