The following side effects are possible with long-term lithium carbonate consumption, including dry mouth, irritable thirst, excessive drinking, excessive urination, constipation, diarrhea, nausea, vomiting, and epigastric pain. There is a possibility of neurological side effects such as fine tremor of the hands, atrophy, weakness, drowsiness, blurred vision, and hyperactive tendon reflexes. It may also cause elevated white blood cells and worsening of the above adverse effects, which may be a precursor to toxicity and should be closely monitored. Due to the low therapeutic index of lithium carbonate, the therapeutic amount and the toxic amount are close to each other, the blood lithium concentration should be monitored during the dosing period to help regulate the therapeutic amount as well as the maintenance amount, and to detect acute toxicity in time. When taking the drug need to pay attention to the large loss of body fluids, such as persistent vomiting, diarrhea, profuse sweating and other conditions, easy to cause lithium poisoning. Low-salt diet is not allowed during the medication, and long-term medication users should regularly check renal function and thyroid function.