Uremic dialysis patients with knee pain at night, usually considered to be hypocalcemia induced, need to timely calcium supplementation, including general treatment and drug therapy. 1. General treatment: in order to promote calcium absorption, it is recommended that patients need to sunbathe more often, avoid staying indoors for too long, and choose the right time for sunbathing. 2. Drug treatment: you can consider taking calcium treatment such as calcium gluconate oral solution, which helps to supplement calcium and relieve knee pain symptoms. There may be other reasons for uremic dialysis patients to experience knee pain at night, so it is recommended to go to a regular hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.