Patients with duodenal mucosal erosion should not drink alcohol, because alcohol can directly stimulate the stomach and duodenal mucosa and lead to the aggravation of the erosion lesion, and the further development of the erosion will reach the muscular layer of the duodenum, which will form a duodenal ulcer. If a duodenal ulcer occurs, it can easily be complicated by bleeding, perforation, or obstruction, so patients are advised to abstain from alcohol, especially during the treatment period when some drugs and alcohol may have adverse reactions. Also drinking alcohol may lead to acute inflammatory changes in the gastric mucosa, such as acute erosive hemorrhagic gastritis, and may directly cause stress ulcers, so it is recommended that patients must strictly abstain from alcohol. For duodenal erosion treatment, mainly give the use of acid-suppressing drugs combined with bismuth or combined rehabilitation new liquid and other proprietary Chinese medicine to promote mucosal repair, the specific medication needs to consult a specialist.