Duodenal ulcer can be cured, duodenal ulcer is the final formation of duodenal mucosa rupture caused by various etiologies. The main clinical manifestations are chronic, periodic, rhythmic epigastric pain and discomfort, and the pain is mainly fasting pain, Helicobacter pylori is the main cause of duodenal ulcer, long-term alcohol consumption and the use of non-steroidal anti-inflammatory drugs, stress state, etc., are common causes of duodenal ulcer. The treatment of duodenal ulcer mainly includes inhibition of gastric acid secretion, protection of gastric mucosa, and if there is H. pylori infection, standard anti-H. pylori treatment should be carried out, and the treatment course should be up to 6-8 weeks. In addition, after the cure, diet should pay attention to a light and easy-to-digest diet, prohibit the consumption of spicy, stimulating and indigestible food, and prohibit the consumption of alcohol.