Pimples on the nose may be caused by acne, rosacea, folliculitis and other diseases, you can take medication for the cause of the symptoms. 1. Acne: Pimples on the nose can be caused by acne. You can use topical retinoids such as retinoic acid ointment or antibiotics such as erythromycin and clindamycin under the guidance of a doctor. 2. Rosacea: The redness, swelling and hardness of pimples on the nose can also be caused by rosacea. You can use antibiotics such as fusidic acid or oral antibiotics such as doxycycline and minocycline as prescribed by your doctor. 3. Folliculitis: The redness, swelling, hardness and pain of pimples on the nose may also be triggered by folliculitis. If it is a bacterial infection, you can use topical antibiotics such as clindamycin gel and mupirocin ointment under the guidance of a doctor, and if it is a fungal infection, you can follow the doctor’s instructions and use topical antibiotics such as ketoconazole cream and econazole cream. Patients with red, swollen, hard and painful pimples on the nose are advised to go to a regular hospital and take symptomatic treatment measures under the guidance of a doctor.