Home quarantine without nucleic acid is not acceptable. Nucleic acid testing is done by PCR amplification, so that a smaller number of viral specimens are significantly increased by amplification, and its accuracy is still relatively high. However, false negatives or false positives may occur due to the effects of sampling, transportation, nucleic acid collection, testing, interpretation of results, and reagents, etc., and there are individual differences in the population, with different viral loads. New coronavirus has the characteristics of general susceptibility of the population, and there is an incubation period, home isolation is to wait for the infected person to show symptoms, and to reduce the risk of transmission of the virus to other people, but some infected people may not show symptoms, or the incubation period is longer, so it is still necessary to actively cooperate with the new coronavirus infection prevention and treatment requirements, and the timing of nucleic acid testing. The timing of release from quarantine and the frequency of nucleic acid testing should be based on local policy.