Once the diagnosis of intestinal atresia is established, surgery should be performed as soon as possible to ensure safety, otherwise it may lead to intestinal perforation and eventually cause peritonitis, infectious toxic shock and death due to multiple organ failure. There are many surgical methods and approaches commonly used at home and abroad, but the ultimate goal is to reconstruct the digestive tract and restore the patency of the intestine. Combined with the specific situation in China (such as affordability, traditional thinking, etc.), the principle of surgery is as much as possible one-time surgical radical treatment. 1.Intestinal resection and anastomosis: The intestinal tube where the atretic lesion is located is resected during surgery, and the proximal end of the atresia is resected appropriately according to the degree of dilatation and the thickness and elasticity of the intestinal wall, usually the resection length is about 10-20 cm, and the severed end is performed as end-to-end anastomosis, end-to-back anastomosis or long oblique anastomosis, etc. Some doctors are also accustomed to trim the proximal end of the atretic intestine to reduce the tube diameter before performing end-to-end anastomosis. 2, a phase of enterostomy: atresia distal intestinal tube dysplasia, there may be functional disorders: such as fetal fecal peritonitis caused by intestinal atresia; distal ileum, colonic atresia caused by fetal colonic changes and other cases should be staged surgery, a phase of enterostomy location should be carefully selected to avoid postoperative diarrhea dehydration and electrolyte disorders, usually about 3 months after fistula surgery again to close the fistula. 3, a phase of external intestinal placement: for higher location of atresia, intestinal perforation, other organ system complications, critical condition and other patients, patients who can not afford a one-time radical surgery or a phase of anastomosis surgery is too risky, should be decisively performed external intestinal placement, in order to shorten the operation time, reduce the surgical blow, avoid surgical contamination, first to save lives. After the postoperative condition is stabilized, re-operation within 3-7 days for intestinal anastomosis or formal enterostomy. 4, intestinal resection “d” anastomosis: surgery found that the patient’s own intestinal conditions are not good, the surgeon is not sure about the first-phase anastomosis, suspicious of postoperative anastomotic fistula or anastomotic severe stenosis, you can use the “d” anastomosis, general high In general, an “inverted” anastomosis is used for high atresia, where the abdominal wall fistula can be placed to drain the dilated proximal intestinal fluid, reduce the pressure in the intestinal cavity, and ensure the healing environment of the anastomosis, and at the same time, the fistula can be inserted and pushed through the fistula for enteral nutrition; a “positive” anastomosis is suitable for low atresia. “In case of anastomotic stenosis or atresia, the distal intestinal dysfunction can be partially replaced by the function of enterostomy without causing serious abdominal distension. The “ding” anastomosis is satisfactory for recovery after surgery, and the fistula can be closed electively if necessary without preservation of the fistula, usually with a cycle of 1-3 months. The patient’s age, low weight, and delicate tissues and organs make the surgery delicate and difficult, and the surgeon’s skills are very demanding, so the patient should choose a specialist hospital with a certain level of technology to avoid difficulties in handling the surgery later.