High uric acid is a metabolic disease caused by an increase in uric acid in the blood due to a disruption in the metabolism of a substance called purine in the body. If there is a problem with any one of these pathways, uric acid will rise. Uric acid rises because it blocks the process of uric acid production in the blood and prevents its excretion. High uric acid can also lead to other diseases. Gout, which used to be relatively rare, has become more common, not only in middle-aged and elderly people, but also in younger people. In clinical practice, the normal value of uric acid for men is 149 to 416 μmol/L. For women, the normal value is 89 to 357 μmo1/L. If the value is exceeded, the uric acid is high. High uric acid is divided into periods, in different stages, there will be different performance. 1. Asymptomatic hyperuricemia: Blood tests can reveal an increased blood uric acid concentration, but no arthritis, hyperuric acid . The clinical symptoms such as stone or kidney stone. This period is not easy to detect unless laboratory tests are done. Asymptomatic hyperuric acid. Hematuria can last for 10 to 20 years, and some may remain free of hyperuric acid … for life. Generally speaking, the higher the blood uric acid level, the greater the risk of developing hyperuric acid. 2. Acute hyperuricemic arthritis: It can develop in all seasons, most often in spring and autumn. Local injury to the joint, overeating, overexertion, cold and wet, certain drugs, infections and surgical procedures can trigger an acute attack. These factors can make the already supersaturated uric acid form needle-like crystals deposited in the synovial fluid, the crystals are regarded as foreigners by the body’s white blood cells and are phagocytosed, and after being phagocytosed, inflammatory factors are released, causing an acute attack. 3. Gouty arthritis: The general attack site is the thumb joint, ankle joint, knee joint, etc. Some patients with long-term gout have attacks on the finger joints and even the soft tissue containing parts of the ear. Acute gout attack site appears red, swollen, hot, severe pain, usually more in the midnight attack, can make people wake up from sleep. In the early stages of gout, attacks are mostly seen in the lower extremities. Gout can and does present with kidney damage. High uric acid, how to control, what do I need to pay attention to? 1, appropriate aerobic exercise, must not do strenuous exercise, so as not to overwork the joints. It is best to choose aerobic exercises such as swimming, tai chi, table tennis and so on, so as to reduce weight. 2, drink more plain water or light tea, the daily urine output should be controlled at about 2000ml is the best. You can use diuretic acid-reducing tea and barley porridge to reduce uric acid, and drink less hot drinks. 3, eat more vegetarian, but not all vegetarian food should eat more, eat more purple eggplant, Shanghai green, lettuce, lotus white. Green vegetables avoid spinach, and then all the legumes should be eaten less or not. Eat more fruit, as well as lemons, etc., a variety of fruits are composed of carbohydrates, so that the body plays a positive role in alkaline, especially more cherries can lower uric acid. 4, eat less meat, but can not eat, because, animal fat and animal protein contained in the protein, is irreplaceable by other foods, but also the body is necessary, but must control the amount! Seafood and animal offal and hot pot are to be strictly forbidden (fish, of course, belongs to the river, you can eat less, and drink more water after eating). Otherwise, the inordinate diet meat, you will be foregone. 5, beer is definitely taboo! Other alcohol is not drunk or strictly limited. 6, develop the habit of soaking feet every day or often with hot water, preferably with a foot bath that can be automatically heated, not less than 20 minutes each time, not more than 30 minutes, can wash the whole body slightly sweaty best. In the foot bath, you can properly add some blood circulation and blood stasis herbs. 7, the combination of work and rest, pay attention to sleep, must not stay up late, relax the mind, optimistic face. Check uric acid every six months, and strive to control it at about 350, gout will not cause damage to any joint. 8, eat more vegetables and drink more water. 9.Eat less beans and foods with high amount of iron. It is recommended to eat more vegetables and fruits and other vegetarian foods, and not to drink alcohol. 10, do not eat seafood, especially squid, cuttlefish, shrimp, crab. 11.Do not eat mushrooms, especially shiitake mushrooms. 12, the diet should be light, less greasy and less salt, eat more coarse grains good. According to the mechanism of uric acid production, we in turn deduce: to prevent and control gout should reduce the production of uric acid, to reduce the production of uric acid to reduce the purines in the body, to reduce the purines in the body to reduce the oxidative decomposition of nucleic acids, and purine intake, while strengthening the elimination of uric acid. Therefore, the measures are: In a normal human body, 1200 mg of uric acid is usually accumulated in the body, and about 600 mg per day, i.e. half of the uric acid in the body, is alternating between old and new. To put it in another way, there are about 1200 mg of uric acid stored in the human body, 600 mg are eliminated and 600 mg are newly produced every day. If we subdivide it further, it means that the 600 mg of uric acid newly produced by the human body every day, 100 mg of which are taken in from food, 500 mg are converted from endogenous purines produced by the decomposition and decay of cells in the body, and as for the 600 mg of eliminated Uric acid, excretion in urine accounts for 450 mg, and excretion in sweat and feces accounts for 150 mg. Under normal circumstances, the body follows this rhythm and law in an orderly manner week after week, but once this balance is broken, regardless of whether the cause is excessive uric acid production or reduced uric acid excretion, there will be an increase in uric acid, leading to hyperuricemia and finally the formation of gout. Prescription uric acid detoxification drugs: The main uric acid detoxification drugs include propofol, sulforaphane and benzbromarone. These drugs can prevent the reabsorption of uric acid by the renal tubules and increase the discharge of uric acid, thus playing a role in reducing the level of uric acid in human body. The side effect is that more uric acid is discharged while other trace elements are also discharged from the body, which can cause low blood sodium, low blood potassium and low blood calcium, so they cannot be used for a long time, and they also have side effects on liver and kidney, so they cannot be used for a long time. Drugs that inhibit the production of uric acid: In 2013, the drug commonly used clinically to inhibit the production of uric acid is allopurinol. This drug is a powerful purine oxidase inhibitor, and it is the only drug that can effectively reduce uric acid production and lower uric acid levels in the body so far. Although allopurinol has fewer adverse effects, it should also be used with caution in people with liver or kidney insufficiency. Drugs that alkalize urine: Sodium bicarbonate and other alkaline drugs have no uric acid-lowering effect but can alkalize urine and increase the solubility of uric acid in the blood, so that uric acid is less likely to accumulate in the urine and form crystals.