Cephalosporin injections can be divided into 5 generations, and there are more than 20 kinds of them in common use, such as cefradine, cefuroxime, cefamandole, cefoperazone, ceftriaxone, cefepime, and so on, which should be used under the guidance of the doctor to avoid adverse reactions. 1.First generation: strong antibacterial effect on gram-positive bacteria, mainly used for respiratory and urinary tract infections, skin and soft tissue infections. Commonly used drugs are cephradine, cefotephine, cefazolin, cefapirin, cefathiamidine, cefazedone and so on. 2. Second generation: slightly weaker than the first generation of Gram-positive bacteria, anaerobic bacteria have a certain effect, mainly used for pneumonia, biliary tract infections, bacteremia, urinary tract infections and so on. Commonly used drugs are cefuroxime, cefamandole, cefotiam, cefonicid and so on. 3. Third generation: it has strong effect on Gram-negative bacteria, and is often used in the treatment of sepsis, meningitis, pneumonia, osteomyelitis and urinary tract infections, and commonly used drugs include cefoperazone, cefotaxime, cefazoxime, ceftriaxone, cefodizime, ceftazidime, cefotaxime, cefpiramide, cefsulodin, and so on. 4. Fourth generation: effective against gram-positive and gram-negative bacteria, commonly used in the treatment of bacterial infections resistant to third-generation cephalosporins, commonly used drugs include cefpirome, cefepime, cefradine and so on. 5. Fifth generation: the same antibacterial spectrum with the fourth generation, the role of stronger, commonly used for complex skin and soft tissue infections, a variety of more serious pneumonia, commonly used drugs are ceflorin, cefepime, etc.. It is recommended that antibiotic use seriously follow the doctor’s instructions, the use of cephalosporin antibiotics within 1 week to avoid drinking alcohol.