Immunosuppressive treatment usually refers to the auxiliary treatment method to weaken or block the body’s immune response ability, chronic eczema immunosuppressive treatment methods are usually based on topical medication, oral drug therapy. 1. External drug treatment: (1) Glucocorticoid drugs: common drugs include mometasone furoate, hydrocortisone and halometasone, which are anti-inflammatory, immunosuppressive and anti-allergic, and can help to treat eczema, and it is recommended to apply the drugs according to the doctor’s instructions. (2) Calcium-regulated phosphatase inhibitors: common drugs include tacrolimus, pimecrolimus, etc., which can inhibit rejection reaction and play the role of immunosuppression, which is effective in the treatment of eczema, and the patients should follow the doctor’s instructions to use the above drugs externally. 2. Oral drug treatment: for patients with serious condition or when other therapies are ineffective, patients can take cyclosporine, methotrexate and other immunosuppressants as prescribed by the doctor, which can reduce the immune response of the body and promote the recovery of eczema. Chronic eczema immunosuppressive treatment is not one, it is recommended that patients go to the hospital to consult a doctor, under the guidance of the doctor to use drugs, do not abuse drugs.