There are no obvious precursors before a patient with brain atrophy passes away, and there is no necessary link between brain atrophy and death. Brain atrophy in general refers to the shrinkage of the brain, mainly Alzheimer’s disease, this disease after diagnosis, the survival period can be up to 10-20 years. Patients often die not because of cerebral atrophy, but because of cerebral atrophy after a long period of bedridden, no contact with the outside world, swallowing function will be impaired, long-term bedridden will lead to some of the fall of pneumonia. In addition, some patients die because of cardiovascular and cerebrovascular diseases induced by old age. Therefore, the patient’s death is often caused by pneumonia or cardiovascular disease, and cerebral atrophy is not necessarily or directly related, and there is no obvious direct signs.