The causes of brain atrophy are complex, and there is a lack of effective treatment measures. Drug treatment mainly focuses on improving patients’ symptoms and slowing down the progress of the disease, and cannot reverse brain atrophy. The following types of drugs are mainly used: i. Drugs to improve cerebral metabolism, usually applying drugs such as olanzapine capsules, cytarabine sodium tablets, cerebral protein hydrolysate tablets, nicergoline, nimodipine and so on, to improve cerebral microcirculation of the patient, promote cerebral metabolism and improve the memory of the patient. Second, use drugs to improve cognitive function, because after brain atrophy patients will more or less have memory loss, slow reaction, dementia. By using acetylcholinesterase inhibitors to increase the concentration of acetylcholine in the patient’s brain and improve the patient’s cognitive function, commonly used are donepezil hydrochloride and strychnine methyl.