If the vulva has blisters, in the clinic the most common cause is due to herpes simplex virus infection caused by the body’s resistance to decline, can lead to viral infections, it is recommended to keep the local clean, in the blisters can be coated with acyclovir ointment treatment, at the same time be sure to strengthen the nutrition, more supplemental proteins, and eat more food containing vitamins, can increase the body’s resistance to enhance the immunity to the disease as soon as possible. This will increase the body’s resistance and improve the immune system, which is conducive to the quick recovery of the disease. It is recommended to wear loose underwear to avoid friction caused by blister breakage, which will aggravate the local pain. Herpes simplex virus infection in the clinical through sexual contact, can be cross-infected, in the clinical laboratory examination did not turn negative before, is not allowed to have sex. If the vulvar blisters are caused by a localized allergic reaction, it is recommended to combine with the clinical history. If it is caused by an allergic reaction, there will be severe local itching, and there is a history of exposure to drugs or other substances, it is recommended that anti-allergy treatment be given, such as oral treatment with restorative medicine.