Enalapril maleate and amlodipine benzenesulfonate do not have which one is better, should be selected depending on the patient’s specific situation, the two can also be used in combination. Enalapril maleate is an angiotensin-converting enzyme inhibitor (ACEI), which can inhibit the formation of angiotensin, inhibit its vasoconstrictor and aldosterone release effects, and play a role in lowering blood pressure, and it is suitable for patients with high blood pressure combined with left ventricular hypertrophy, history of myocardial infarction, diabetic nephropathy, proteinuria, etc. It should be noted that it is contraindicated in patients with high blood pressure. It should be noted that enalapril maleate is contraindicated in people who are allergic to this drug, have bilateral renal artery stenosis, and have severe renal impairment. The use of the drug may cause dizziness, headache, drowsiness, dry mouth, skin rash and other adverse reactions. Amlodipine benzenesulfonate is a dihydropyridine calcium channel antagonist (CCB), which can dilate peripheral blood vessels, relieve angina pectoris, and is more suitable for volumetric hypertension, such as simple systolic hypertension, as well as the combination of atherosclerosis in patients. Amlodipine benzenesulfonate is contraindicated in people who are allergic to this drug and should be used with caution in people with impaired liver function. Adverse reactions such as headache, edema, palpitations and flushing may occur after use. To summarize, there is no absolute better between the two drugs, should be selected according to the patient’s situation, can also be used in combination when necessary, should be used under the guidance of a doctor.