Stage II rectal cancer is not scary, the five-year survival rate can reach 70% through surgical treatment, radiotherapy and chemotherapy. Rectal cancer is a common malignant tumor in China, which can be divided into upper rectal cancer and lower rectal cancer with the boundary of peritoneal fold. The severity of rectal cancer cannot be generalized, and it needs to consider the patient’s tumor stage, tumor grading, patient’s physical condition, treatment methods and means. Five-year survival rate is commonly used in clinical practice to assess the survival of rectal cancer patients. For stage II rectal cancer, the five-year survival rate is 70%. The treatment methods of rectal cancer are mainly divided into surgery, radiotherapy, chemotherapy and so on. Surgical procedures for rectal cancer can be categorized into three types: the Miles procedure, the Dixon procedure, and the Hartman procedure. Neoadjuvant chemotherapy is recommended for stage II low and intermediate rectal cancer, and commonly used drugs include oxaliplatin, calcium folinate, fluorouracil and so on. Radiotherapy can be preoperative radiotherapy and postoperative radiotherapy. Preoperative radiotherapy can be used for stage II rectal cancer. Preoperative radiotherapy can shrink the tumor and reduce the stage, improve the resection rate of surgery and reduce the local recurrence rate. It is suggested that patients should consult the doctor in time and have standardized and individualized treatment under the guidance of professional doctors.