1.When blood clots, vomiting blood, fresh blood or tarry stools, bleeding gums, blood in sputum, purpura, chest pain, pelvic pain, headache, dizziness, prolonged bleeding after minor trauma or any symptoms of hepatitis (darkening of urine, itching of skin, jaundice, lightening of stool color, clay color) occur, the drug should be stopped immediately and contacted with the doctor. 2.Take the medication at the same time every day, the dose and brand of the medication should not be changed without the doctor’s permission. 3. Do not take other medications, including aspirin and cold medications, without your doctor’s permission. These drugs can interfere with the effects of Warfarin and cause health hazards. 4.Influenza vaccine makes the effect of anticoagulation increase, check for bleeding within one month of vaccination. 5.Fever, climate fever, malnutrition and diarrhea can prolong the clotting time causing bleeding. 6.Keep a balanced, relatively regular diet and good eating habits, and keep in mind to eat less high-fat diet and foods rich in vitamin K such as: cabbage, cauliflower, asparagus, lettuce, green radish, fish, liver, etc. 7, avoid alcohol abuse. Drinking alcohol can accelerate the metabolism of Warfarin and shorten the bleeding time. Avoid trauma and bleeding as much as possible. 8.Use a soft toothbrush, shave with an electric razor, wear gloves when cultivating flowers and plants, and check with your doctor before participating in sports to see if your physical condition is unfit for exercise. 9, quit smoking or smoke as little as possible, smoking can speed up the metabolism of the drug need to adjust the dosage. 10.Warfarin can cause miscarriage, stillbirth and fetal malformation, please tell your doctor if you are pregnant or planning to get pregnant. 11.Patients should tell the doctor that they are taking Warfarin when they visit the doctor, and carry a medical certificate with them to show that they are receiving Warfarin treatment.