Patients with insomnia and wasting are mainly related to poor mental conditions, endocrine diseases, cardiovascular diseases and other reasons. Patients should go to the hospital to clarify the cause and carry out targeted treatment.1. Poor mental condition: excessive mental tension, anxiety, stress, mental disorders and other conditions can cause the patient’s gastrointestinal tract digestive function to be affected, resulting in insomnia and emaciation. Patients can relax, light diet, adequate rest, the symptoms caused by this situation can usually be gradually recovered after eliminating the cause. In addition, patients can drink sleep-aiding and appetizing drinks in daily life, such as hot milk and sour date water, etc.; 2. Endocrine diseases: endocrine disorders caused by endocrine diseases can lead to insomnia and weight loss, such as diabetes and hyperthyroidism. Patients can take gliclazide, methimazole and other drugs under the guidance of doctors. Patients should ensure rest and avoid staying up late to avoid aggravating the condition; 3. Cardiovascular diseases: hypertension, arrhythmia, heart failure and other diseases can lead to cortical disorders, which in turn lead to insomnia, wasting and other symptoms. Patients should follow medical advice to take the appropriate drugs for treatment. In addition, in daily life, more fresh fruits and vegetables, such as carrots and oranges, should be consumed to reduce cardiovascular and cerebrovascular pressure.