Progesterone can be taken on an empty stomach to make the drug better absorbed, so that it can make the most of its effects. Progesterone does not necessarily have to be taken on an empty stomach, can be taken 30 minutes before meals, can also be taken apart from the meal time, progesterone has a certain irritation of the gastrointestinal tract, may cause patients to appear gastrointestinal reactions, if patients usually have chronic gastritis and other diseases, in order to avoid progesterone irritation of the gastric mucosa, can be taken 30 minutes after meals, can prevent patients from nausea, vomiting and so on. During the progesterone to pay attention to drink more water, and diet should pay attention to light, easy to digest food, it is best not to eat spicy and irritating food to the gastrointestinal mucosa, so as not to aggravate the drug appears gastrointestinal adverse reactions.