The most effective medication for treating itchy skin in the elderly does not exist clinically; itchy skin in the elderly may be associated with contact dermatitis, systemic diseases, eczema, and other factors. It can be treated by taking oral cetirizine, treating systemic diseases, and applying mometasone furoate ointment. 1. Contact dermatitis: elderly people’s skin contact with animal fur, pollen and other allergens or irritants produce an inflammatory reaction, resulting in itching. It can be treated with oral anti-allergic drugs such as cetirizine and epinastine. 2. Systemic diseases: such as diabetes, kidney disease, etc. will lead to metabolic disorders in the body, which may cause itchy skin. As long as the active treatment of systemic diseases, itching will gradually improve. 3. Dry eczema: due to the elderly sebaceous gland secretion is reduced, dry skin leads to dry eczema, easy to cause itchy skin. It can be treated by local moisturizing and applying glucocorticoids such as mometasone furoate. It is recommended that patients consult the dermatology department of a regular hospital and follow the doctor’s instructions to use the correct treatment.