Vulvar leukoplakia can be treated with estrogen ointment or glucocorticoid drugs such as florazepam ointment and cotrimoxazole ointment under doctor’s supervision, and there is no single drug that is the best. Vulvar leukoplakia is localized vulvar dystrophy, related to estrogen deficiency, you can apply estrogen ointment locally to promote the improvement of symptoms. In addition, vulvar leukoplakia localized with inflammatory reaction, you can use glucocorticoid drugs anti-inflammatory treatment, such as fluoxetine ointment, cotrimoxazole ointment and so on. In addition, pay attention to personal hygiene during the rubbing period, keep the vulvar area clean and dry, and pay attention to light diet, do not eat spicy food, to prevent making the inflammation worse. If the patient has vulvar leukoplakia, it is recommended to consult a doctor in time, under the guidance of the doctor, the use of the correct medication to carry out treatment, so as not to delay the treatment.