Pain in the adnexa may be caused by inflammation of the adnexa, such as tubal inflammation or ovarian inflammation. 2. It may also be caused by adnexal cysts, such as ovarian cysts, corpus luteum cysts, inflammatory masses of the fallopian tubes that twist or rupture. 3. 5. When women suffer from appendicitis, they may also experience pain. Therefore, when a woman has pain in the adnexa, she must go to the hospital for gynecological ultrasound, blood tests and human chorionic gonadotropin levels, and take the appropriate medication or surgery according to the different causes, the effect is better.