Having a cholesteatoma for more than 10 years is not considered serious, but developing an infection is more serious. Cholesteatoma is a benign disease, mainly due to the keratinization of the skin of the ear canal, shedding necrotic epithelium and thus can not be discharged, the accumulation of the formation of cholesteatoma, but also for congenital cholesteatoma may be due to the amniotic fluid into the epithelial tissue resulting from smoking, diabetes mellitus, frequent pulling out of the ear, wearing hearing aids and so on may induce cholesteatoma; the clinical symptoms of ear stuffiness, ear pain, hearing loss and so on. For the treatment of cholesteatoma, surgery and medication can be used, and surgery is not usually used for small cholesteatoma, which generally does not cause great harm to human body, but may be complicated by other symptoms, and when the pressure of bile duct increases, it will lead to the rupture of cholesteatoma, which will lead to the infection, and then it will be more serious. If you feel unwell, you should go to the hospital in time and consult your doctor.