When folliculitis turns into hard bumps in the later stages, they may be nodules or cysts that have formed because the inflammation has not completely subsided, or they may be mechanized reactions that remain after the inflammation has subsided. This can be managed with medication, physical therapy, or surgery. If the patient’s hard lumps are accompanied by redness, swelling and pain, indicating that the inflammation of folliculitis has not completely subsided, you can use topical antibiotic drugs, such as mupirocin ointment, fusidic acid cream, etc.; at the same time, you can also take oral medication to carry out systemic treatment, such as minocycline, doxycycline, etc., to promote local inflammation to subside and absorb. If there is no redness, swelling and pain in the hard lumps, it is considered to be the mechanization reaction after the inflammation subsides, and it can be absorbed and subsided by itself after a period of time. If it does not subside for a long time, it can be treated by local injection of glucocorticosteroids, such as Triamcinolone acetonide, etc.; it can also be improved by physical therapy, such as red and blue light irradiation, etc., to promote the recovery of inflammation, thus promoting the dissipation of the hard lumps; and it can also be surgically removed from the localized mechanized cysts. If the hard lumps in the area reappear to be infected, such as redness, swelling, pain, localized fluctuating sensation, etc., it is recommended to make a timely surgical incision and drainage, and give antibiotic treatment. When the patient’s skin folliculitis becomes hard lumps in the later stage, it is recommended to go to the regular hospital for timely examination and active treatment. The above medications and treatments should be used under the guidance of a professional doctor to avoid adverse consequences.