Not all antihypertensive drugs can cause insomnia. Common antihypertensive drugs that can cause insomnia include propranolol, furosemide, and colistin. Side effects of propranolol include affecting the nervous system, which may lead to frequent nightmares, or worse, hallucinations and other conditions. Diuretics lower blood pressure by removing water and salt from the body and can also interfere with sleep if taken at night causing frequent urination. Colistin, a central nervous system antihypertensive drug, is currently used less clinically, but it has been found to be able to cause insomnia among the side effects of the drug. Although antihypertensive drugs have adverse effects, but compared with lowering blood pressure is still more beneficial than harmful, the doctor will also be adjusted according to the actual situation of the patient’s medication, the patient needs to follow the doctor’s instructions, take medication at regular intervals.