The time of excretion of hormonal drugs from the body is closely related to the type of drug, which is usually excreted from the body after a few hours to a few days. The residence time of hormonal drugs in the body is not related to the concentration of the drug, but depends on the half-life of the drug, which is the rate of excretion, biotransformation and storage of the drug in the body. Different drugs have different half-lives, for example, glucocorticoids can be divided into three categories: long-acting, medium-acting and short-acting, and doctors will choose drugs with different efficacy for different patients’ different conditions. Therefore, hormones can be discharged from the body within a short period of time and their effects on the body may disappear within six months, so patients do not need to worry too much about this, but long-term use of hormones will produce adverse reactions and the recovery time is relatively slow. In daily life, to speed up the discharge of hormones from the body, we can increase the amount of water we drink, increase physical activity and eat more vegetables and fruits to speed up the metabolism of the body and promote the discharge of hormones.