Large red bumps in the armpits may be caused by boils, soft fibromas, sebaceous cysts and other diseases, which are usually treated with medication, physical therapy and surgery. 1. Boils: acute purulent inflammation of the deep part of the hair follicle and surrounding tissues, often induced by Staphylococcus aureus. It can be manifested as large red bumps in the armpits. Local topical mupirocin ointment, clindamycin gel, etc. If the symptoms are serious, oral antibiotic drugs, such as cefuroxime, doxycycline, etc. can be taken at the same time. 2. Soft fibroma: soft fibroma may be related to obesity, viral infection and other factors, preferably occurring in the neck, armpit, manifested as a high skin surface of the tibial proliferation, the color is generally brown, red or normal skin color. Physical therapy such as freezing and laser can be given, and surgical excision can be taken if the volume is large. If the tumor is small, physical therapy can be used, such as laser therapy, liquid nitrogen cryotherapy, electrocautery therapy, etc.; if the tumor is large, surgical ligation or excision can be used for treatment. 3. Sebaceous cysts: due to axillary sebaceous gland duct blockage, resulting in sebum retention to form cystic swelling, if secondary infection, will lead to the formation of red bumps, this time the need for anti-infective treatment, such as topical fusidic acid cream, mupirocin ointment, oral roxithromycin, cephalosporin and other medications, to be controlled by inflammation and then surgical excision of cysts. The symptoms of large red bumps in the armpits alone can not accurately determine the cause of the disease, but also need to be combined with the characteristics of the medical history and examination results to make an accurate judgment, it is recommended to clarify the cause of the disease under the guidance of a doctor. Drugs should be used in accordance with medical advice.