Sleep disorders are closely related to blood sugar

  With increased social pressure and lifestyle changes, the incidence of diabetes is spiking; and sleep problems are particularly prominent in modern life. The United States, Japan and other developed countries are increasingly concerned about the relationship between sleep and abnormal glucose metabolism.  The status of blood glucose control to meet the standard is not optimistic, poor lifestyle has a great impact, sleep problems are prominent The incidence of diabetes in China is rapidly increasing, the incidence of adult diabetes is up to 9.7%, and pre-diabetes up to 15.5%. It is well known that the development of diabetes complications is closely related to the control of glycated hemoglobin, and the results of the National Health and Nutrition Examination Survey (NHANES) found that the attainment rate of glycemic control (A1C <7.0%) for diabetes from 2007 to 2010 was 52.5%, while the overall attainment rate in China was 41%. The researchers found that the lower rate was associated with a number of factors, including poor lifestyle, which accounted for 45%. Among them, sleep problems are particularly prominent. 2006 All Sleep Association survey found that 60% of China's urban population has sleep disorders, and more common among diabetic patients, the study found that 60% of elderly type 2 diabetic patients have sleep disorders, manifested as late sleep time, early awakening, insomnia, etc.; especially with the change of modern lifestyle, such as social, Internet, etc., this problem is more and more prominent.  Sleep disorders are closely related to abnormal glucose metabolism The NHANES cross-sectional study in the United States analyzed the relationship between sleep quality and sleep duration and glucose status. The study investigated 2,285 individuals over 30 years of age without a diagnosis of sleep disorders, including difficulty falling asleep, early awakening, and persistent sleep difficulties, by means of a sample questionnaire in the 2005-2008 NHAES. The primary endpoint was clinically determined undiagnosed prediabetes and diabetes. Results from logistic regression analysis showed that less than 5 hours of sleep per night was associated with clinically determined prediabetes after correction for sociodemographic and health behaviors. Persistent sleep difficulties and early awakenings more than 5 times per month were also significantly associated with it. Difficulty falling asleep and more than 9 hours of sleep were not associated with diabetes. A prospective study of 3570 local government employees by Kita et al. in Japan also found that those who slept less than 5 hours had an OR of 5.37 for the development of diabetes compared to those who slept more than 8 hours, and the results of this study were published in the journal Diabetes care. The results of a 2-year follow-up of 1136 cases of IGR by scholars from Zhejiang University in China also found that there was indeed a causal relationship between sleep quality and the risk of developing diabetes in the IGR population. The above studies fully confirm that sleep disorders are closely related to abnormal glucose metabolism.  Sleep disorders increase insulin resistance The mechanism by which sleep affects blood glucose is unclear and is presumed to be related to abnormal secretion of hormone levels and increased levels of insulin resistance. Swedish scholars found that reversal of sleep and meal times altered the 24-hour secretion patterns of IGFBP1, glucose, insulin, and GH; a study at the University of Helsinki, Finland, found that people with more sleep-related complaints had more pronounced insulin resistance, higher fasting insulin levels and post-glucose load insulin glucose levels, and higher HOMA-IR index and lower insulin sensitivity index. The more sleep problems there were, the more likely their IR increased, and this correlation remained after correction for confounding factors. Sleep problems were not correlated with insulin deficiency.  In conclusion, sleep disorders are closely related to diabetes mellitus, mainly associated with increased insulin resistance, and whether improving sleep can improve insulin resistance does lead to better glycemic control and delay the progression of complications.