Erythromycin eye ointment and levofloxacin eye drops can be used together, but the two need to be spaced out as much as possible, rather than being put into the eye at the same time. Erythromycin ophthalmic ointment is a cream medication, while levofloxacin eye drops is a liquid medication, the two can be used together, but it is best not to put the drops into the eye at the same time. Because of the small size of the conjunctival sac, if the two are put into the eye together, it is easy to waste the medicine. Usually levofloxacin eye drops can be used during the day and erythromycin eye ointment can be used at night before bedtime. Both erythromycin eye ointment and levofloxacin eye drops belong to the antibiotic group of medications that can treat diseases such as conjunctivitis caused by infections and other reasons. Erythromycin eye ointment can be used to treat eye conditions such as conjunctivitis, blepharitis, external eye infections, and trachoma. This eye ointment needs to be applied to the inside of the eyelid, usually two to three times a day, and is more effective when applied at bedtime. Levofloxacin Eye Drops belongs to the quinolone antibiotic class and can be used to treat infectious diseases such as conjunctivitis, keratitis, blepharitis, and dacryocystitis, and works by dropping into the conjunctival sac. It is recommended that patients use both eye drops under the guidance of a doctor, do not use them without authorization, to avoid causing eye discomfort.