When lung cancer reaches advanced stage, it may still be more painful. Like other malignant tumors, there may be multiple metastases and failure of important organs at advanced stage, for example, firstly, respiratory failure, there will be symptoms such as chest tightness, chest pain, coughing, coughing and fever. If lung cancer has bone metastasis, there will be bone pain and pathological fracture; liver metastasis may have symptoms such as right upper abdominal distension and discomfort, as well as ascites and jaundice; if there is brain metastasis, there will be symptoms such as increased intracranial pressure, nausea, vomiting, dizziness and headache. At the advanced stage, there is no too good treatment, only to try to reduce the pain and prolong the survival treatment. If the pain is heavy, strong painkillers, such as oxycodone and morphine, can be applied. In late stage, if you can use anti-tumor therapy, such as radiotherapy, chemotherapy, targeted drug treatment, shrink the primary tumor lesions and control metastatic lesions, it is also possible to reduce the pain.