Hepatitis B virus is mainly transmitted through blood, and for adults, hepatitis B infection is possible through sexual intercourse, pedicure, tattoo, earring piercing, and sharing razors and toothbrushes. Parents in China have generally raised their awareness of protection for children, but most adults have little awareness of self-protection, and some do not see the need for hepatitis B vaccination. It should be said that vaccination against hepatitis B is not only for your own protection, but also for the protection of your family and future generations. In order to be responsible for yourself, your family and society, adults should take the initiative to receive the hepatitis B vaccine. People who have not received hepatitis B vaccine must complete three doses of hepatitis B vaccine according to the national immunization program. The higher the titer of hepatitis B surface antibody in the serum, the stronger the protection and the longer it lasts. When the titer of hepatitis B surface antibody is less than or equal to 10 IU/ml, it is difficult to provide protection and a booster vaccination should be given as soon as possible. Some people do not produce antibodies after vaccination, and some people are at risk of hepatitis B infection because the dose of hepatitis B vaccine they received in the past was too low and their antibodies soon began to decline, so they are not protected. The 60-microgram recombinant hepatitis B vaccine (yeast) is an independent vaccine developed with advanced technology and equipment from Merck in the United States for susceptible people aged 16 years and older who do not have antibodies or have low antibodies after hepatitis B vaccination. It is especially suitable for obese people, smokers, partners and family members of hepatitis B carriers, and newlyweds who do not produce antibodies after regular low-dose hepatitis B vaccination. 60 micrograms of hepatitis B vaccine requires only one dose, and the antibody positive rate can reach 83.26% after one month, and the antibody level is much higher than other doses of hepatitis B vaccine, and the high antibody level can be maintained in the body for more than 15 years. Adults do not need to have a two-to-one test before vaccination Adults do not need to have a two-to-one test before receiving the hepatitis B vaccine. Because the components of hepatitis B vaccine are mainly HBV shell protein expressed by genetically recombinant yeast cells, i.e. HBsAg made after purification, addition of aluminum hydroxide adjuvant and inactivation treatment, it is non-infectious and does not cause infection to the organism, and it is safe for people who have or have not been infected with hepatitis B virus to receive hepatitis B vaccine.