Thyroid nodules can be detected by both the penta and hepta tests. Thyroid 5 is mainly to detect whether the thyroid function is abnormal, whether there is hyperthyroidism or hypothyroidism, and Thyroid 7 is added on top of this to measure the thyroid autoantibodies to determine whether there is autoimmune disease. Different hospitals may have different testing programs, so it is recommended to consult your doctor. Thyroglobulin 5 includes total T3, free T3, total T4, free T4 and TSH, which mainly detects whether the thyroid function is abnormal and whether there is hyperthyroidism or hypothyroidism, but some hospitals also detect free T3, free T4, TSH and autoimmune antibodies (TPOAb, TGAb). Thyroglobulin 7, on the other hand, includes total T3, free T3, total T4, free T4, TSH, TPOAb, TGAb, which can not only determine whether you are suffering from hypothyroidism or hyperthyroidism, but also help to determine the presence or absence of autoimmune thyroid disorders, such as Graves’ Disease, Hashimoto’s Thyroiditis, and so on. Thyroid nodules can occur at the same time with the above diseases, but the chances are small, so you can consult your doctor to choose the appropriate program.