Mucus in the stool may be caused by ulcerative colitis, irritable bowel syndrome, colon cancer, etc. After diagnosis, appropriate treatment should be carried out, including medication such as mesalazine, bifidobacteria, etc. and surgical treatment. 1. Ulcerative colitis: it can be treated with medicines such as mesalazine and azathioprine. 2. Irritable bowel syndrome: for irritable bowel syndrome, medication such as bifidobacteria, lactobacillus tablets and other medications can be used, and when there are obvious symptoms of abdominal pain, medication such as mebeverine can also be used. 3. Colon cancer: it is a malignant lesion, which will make the patient have the symptom of stomach distension and mucus in stool. After diagnosis, surgical treatment can be considered, such as right hemicolectomy and transverse colon resection. During the period of treatment, patients should follow the doctor’s instruction, apply medicines reasonably for treatment, take good care of themselves after surgery, and go to the doctor regularly for rechecking.