There are many factors that affect patients with crohn’s disease, first of all related to the etiology of crohn’s disease, some crohn’s combined with brain dysplasia, and others are part of the inborn metabolic abnormalities disease, often combined with mental retardation. The impact of different types of crohn’s on intelligence is also different. Primary crohn’s such as amniotic crohn’s and benign partial crohn’s in children often have little impact on intelligence. Infantile spasms, a type of amniotic stroke, has more than 90% intellectual impairment. The frequency of seizures also has an effect on intelligence, and the more frequent the seizures, the greater the incidence of mental retardation. In one study, in pediatric amniotic stroke, if there are less than 11 even seizures per year, mental retardation accounts for only 28%; in children with daily seizures of amniotic stroke, mental retardation is as high as 76%. There is also a close relationship between the age of onset and intellectual development, the younger the age of onset, the greater the impact on intelligence. According to the survey, more than 70% of children with onset of the disease within one year of age are combined with mental retardation, while only about 40% of children with onset of the disease between the ages of 9 and 15 are mentally retarded. A large number of long-term use of anti-amniotic drugs, its side effects may affect the patient’s intelligence, but the correct anti-amniotic treatment does not have a significant impact on intelligence. The development of intelligence can also be improved if the seizures are quickly controlled or reduced after treatment of pediatric amniotic stroke. How can family members act as little guardians for epilepsy patients? 1, to the patient and family members to promote the basic knowledge about the prevention of epilepsy triggers, need to pay attention to avoid the following factors that cause sudden seizures: such as sudden mental stimulation, strong sound, strong light stimulation, cold, cold, rain, excessive change of air, excessive drinking, overwork, hunger or overfed, etc. 2, the active cooperation of family members and patients is the key to treatment, encourage patients to adhere to treatment, under the guidance of physicians for long-term medication, and never stop or change medication on their own. At the same time, further search for the cause of the disease, in order to deal with the cause. 3. Do not engage in overhead work, diving, driving or dangerous machinery operation, etc. Keep optimistic; live and work regularly; if you find any changes in your condition, you should follow up at any time. 4. If a pregnant woman takes anti-epileptic drugs for a long time, it is better to terminate the pregnancy to avoid fetal malformation. 5. Ask the patient to carry a disease card (indicating name, diagnosis, address, telephone number, etc.) with him/her so that he/she can be contacted in case of a seizure and be easily rescued. Do not go out alone if the seizure is not well controlled to avoid drowning, burns, falls and other accidents. 6, epileptic patients should not drink a lot of cold water and cold drinks in summer to prevent the concentration of drugs in the blood from decreasing, reducing the effectiveness of treatment.